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The putative Drp1 inhibitor mdivi-1 is a reversible mitochondrial complex I inhibitor that modulates reactive oxygen species
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Several mutations have been described, the most common being R1441H , R1441G , R1441C , and G2019S , which cause a loss of dopaminergic neurons while altering processes such as cytoskeletal function, the lysosomal system, protein synthesis, and vesicle transport [17,18]
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